Latrunculin A Depolymerizes Actin Filaments by Binding Terminal Subunits and by Sequestering Actin Monomers
نویسندگان
چکیده
منابع مشابه
Actin-latrunculin A structure and function. Differential modulation of actin-binding protein function by latrunculin A.
Latrunculin A is used extensively as an agent to sequester monomeric actin in living cells. We hypothesize that additional activities of latrunculin A may be important for its biological activity. Our data are consistent with the formation of a 1:1 stoichiometric complex with an equilibrium dissociation constant of 0.2 to 0.4 micrometer and provide no evidence that the actin-latrunculin A compl...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2019
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.59.192